Calcineurin inhibitors (CNIs) are a class of immunosuppressive drugs that have revolutionized the field of transplantation and the management of certain autoimmune diseases. These drugs work by inhibiting the activity of the enzyme calcineurin, a critical regulator of T-cell activation and the immune response. The discovery and development of calcineurin inhibitors have significantly improved the success rates of organ transplantation and provided new treatment options for patients with ... Read more