Steroid 17 Alpha Hydroxylase17, 20 Lyase actively synthesize steroid hormone with help of a single enzyme P450c17 whereas different isozymes of P450c17 mediate activities of Steroid 17 Alpha Hydroxylase17, 20 Lyase in testis and adrenal glands. Steroid 17 Alpha Hydroxylase17, 20 Lyase deficiency rarely occurs and amounts to very few cases of congenital adrenal hyperplasia that exists with symptoms such as sexual infantilism and hypertension. The primary cause is CYP17A1 gene’s loss of ... Read more
