Hemostasis is the process where platelets, blood vessels, and coagulation factors act together to arrest bleeding. Hemostasis occurs by the coagulation process where blood is solidified from liquid to gel state through serial enzymatic steps. During the hemostasis process, thrombin plays the role of key enzyme. Thrombin is an enzyme which is synthesized from precursor glycoprotein called prothrombin.

During the clotting process, proteolytic cleavage of prothrombin results in thrombin ... Read more