Protein A resin is derived from the bacterial cell wall of Staphylococcus aureus. The bacterium naturally produces protein A, which binds strongly to the Fc region of immunoglobulin G (IgG) molecules from other organisms. In the early 1970s, scientists discovered this unique binding property of protein A and began work to recombinantly express it as a purification tool.
By genetically fusing protein A to agarose or ... Read more
