Primary sclerosing cholangitis (PSC) is a chronic and rare liver disease characterized by progressive inflammation and scarring of the bile ducts within the liver. PSC causes bile duct injury which leads to bile-duct narrowing and bile build-up. If left untreated, it can lead to serious complications such as liver failure, cancer and ultimately liver transplant may be required. The disease often occurs in patients with ulcerative colitis, an inflammatory bowel disease. Medications help to ... Read more