Cancer researchers have long sought new therapeutic strategies to attack cancer cells while sparing normal cells. One promising avenue is targeting DNA repair pathways that are crucial for cancer cell survival but dispensable in healthy cells. PARP (poly polymerase) inhibitors are a class of anti-cancer drugs that do precisely this - they exploit DNA repair defects in cancer cells to selectively kill them. In this article, we will explore the mechanisms of action of PARP inhibitors and their ... Read more
