Polyoxyethylene 40 stearate is soluble in ethylacetate, methanol, ethanol, and water. It is used in a study to investigate its effects on multidrug resistance (MDR) and to assess the phase behaviours of micro-emulsion to produce nanostructured drug-loaded lipid carriers. It enhances antitumor activity and modulates multidrug resistance of vinblastine sulphate, which is one of the major hurdles limiting the efficacy of cancer chemotherapy.
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