The C-terminal domain has epoxide hydrolase activity and acts as on epoxides such as oxiranes and alkene oxides; and arene oxides. Bifunctional epoxide hydrolase 2 plays an instrumenetal role in xenobiotic metabolism through degrading potentially toxic epoxides. In addition, bifunctional epoxide hydrolase 2 also decides steady-state levels of physiological mediators. Meanwhile, the N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9, 10-phosphonooxy- ... Read more
