Alpha synuclein is involved in transmitter regulation at the time of synapse and is found throughout the body. It is abundantly present on brain and is encoded by SNCA gene. It restricts synaptic vesicles mobility, thereby attenuating recycling of synaptic vesicles and release of neurotransmitters. Clinical diagnosis of Parkinson’s disease is made at very later stage where nerve cells have already undergone serious damage. Parkinson’s disease results in irreversible change in body which ... Read more
