Alpha emitters are radioactive particles or isotopes that release alpha particles during radioactive decay. They are primarily used in targeted alpha therapy (TAT) for cancer treatment. In TAT, alpha emitter isotopes are attached to molecules that specifically target tumor cells. When internalized by cancer cells, alpha particles can damage DNA and induce cell death. Compared to other radiation therapy, TAT is more effective in treating cancers with minimal damage to surrounding healthy ... Read more
Alpha emitter therapy, also known as alpha radionuclide therapy, uses radioactive particles that emit alpha particles to treat cancer. These alpha emitters include radionuclides such as radium-223, actinium-225, and bismuth-213 that can be attached to carriers like antibodies, peptides, small molecules and delivered directly to the tumors to irradiate cancer cells from inside while sparing surrounding healthy tissues. This therapy holds promise for treating both primary cancers as well as ... Read more
What are Alpha Emitters?
Alpha emitters are radioactive elements that emit alpha particles as they decay. Alpha particles are made up of two protons and two neutrons, making them essentially helium-4 nuclei. Some common alpha emitting nuclear isotopes include uranium-238, polonium-210, radium-226 and thorium-232.
Properties of Alpha Particles
Alpha particles have a +2 charge and travel at about 15% the speed of light. They have a ... Read more
The alpha emitter market comprises of alpha emitting isotopes which are used as therapeutic agents for cancer treatment. Alpha particles have high mass and positive charge, which makes them highly effective in damaging cancer cells. Alpha emitting isotopes such as radium-223 (Xofigo) and actinium-225 are majorly used to treat cancers such as prostate cancer, bone metastases and other cancers. The ability to effectively destroy cancer cells with minimum damage to surrounding healthy tissues ... Read more