Clinical studies reveal sildenafil side effects are mild and usually well tolerated
Since its release in 1998, sildenafil has successfully treated more men with erectile dysfunction (ED) than any other medication. It remains a highly sought-after choice and many years of clinical studies have shown it is a safe medication to use. Common side effects are usually mild and only affect a small percentage of users.
The safety of sildenafil citrate
A study was conducted to assess the incidence of sildenafil side effects among a diverse group of patients from a university-based practice. The study involved 256 patients who were questioned in a clear and detailed manner about the occurrence of various side effects. Sildenafil citrate was tested in the study and men can now also order sildenafil online.
The researchers found that the most common side effects were facial flushing, headache, nasal congestion and heartburn. All adverse reactions were short-lived and mild in nature. In this study, almost 70 percent of the participants experienced no side effects and no one withdrew because of the severity of side effects. The researchers concluded that sildenafil citrate remains a safe and well-tolerated treatment for ED.
Sildenafil can treat sexual side effects caused by other medicines
Other medications can cause sexual side effects such as erectile dysfunction (ED). This situation can be frustrating but it is usually important for a patient to continue taking their medication to treat their relevant condition. Some of the most common types of medications that cause sexual side effects include:
- antidepressants
- non-steroidal anti-inflammatory drugs (NSAIDs)
- antihistamines
- antihypertensive medications
Sexual side effects are common with the use of antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs). This is known as antidepressant-associated sexual dysfunction (AASD) and men who are taking antidepressants often experience ED. Patients may consider discontinuing the use of their antidepressant medication but it is usually important to continue treatment to prevent a relapse of depressive symptoms.
The efficacy of sildenafil in treating AASD
A study that involved 90 men with major depression in remission and sexual dysfunction associated with antidepressant use was published in 2003. The objective of the study was to assess the efficacy of sildenafil citrate in men with sexual dysfunction associated with selective and non-selective serotonin reuptake inhibitor (SRI) antidepressants.
The average age of the participants was 45 and they were separated into two groups. The one group received sildenafil and the other group were given placebo which is an inactive substance so researchers can compare the difference. These tablets were to be taken before sexual activity over the course of six weeks with a flexible dose starting at 50mg and adjustable to 100mg.
The study showed that 54.5 percent of the men taking sildenafil reported significant improvements in erectile function. The researchers used self-administered questionnaires to determine the outcomes. Only 4.4 percent of the patients who used placebo reported improvements in erectile function. Other aspects that improved considerably with the use of sildenafil in comparison to placebo included the following:
- arousal
- ejaculation
- orgasm
- overall satisfaction
How sildenafil improves erectile function
When an erection happens, the penis fills with blood and this is what gives it rigidity. Erection difficulties happen when blood supply to the penile region is disrupted. Sildenafil works by boosting levels of nitric oxide in the body. Nitric oxide is a naturally occurring chemical that causes blood vessels to relax and expand and as a result, blood flow improves.
How to take sildenafil for best results
One tablet should be taken 30 to 60 minutes before planned sexual activity. This allows the medication enough time to enter the bloodstream and start working. Taking sildenafil with a large or fatty meal can affect the absorption rate so men are usually advised to wait about two to three hours after a meal before taking a tablet.
Sildenafil stays effective for about four to six hours and contrary to what some people may think, this does not mean an erection will be present for this length of time. This medication works in response to sexual stimulation so it simply restores erectile function while it is effective in the body. It gives the user an adequate amount of time to initiate sexual activity without feeling rushed.
Sildenafil can be ordered online
Men who are looking to purchase sildenafil online can visit www.sildenafil4uk.com and place an order. This online pharmacy sources high-quality medication from Teva Pharmaceuticals and Dr. Reddy’s Laboratories. Sildenafil is the more affordable generic version of Viagra so it has the exact same safety, strength and sildenafil side effects. Since the patent for Viagra expired in 2013, other manufacturers have been permitted to produce and sell sildenafil citrate.
Ordering online gives you assured access to these bioequivalent meds, in a safe and secure environment.