The increasing need for animal alternatives in medical research and growing government funds and grants for studies are the prime factors strengthening the organ-on-chip market, globally.

Based on type, the organ-on-chip market is broadly classified into liver, heart, lung, kidney, and intestine-on-chip. Among these, in 2017, the liver-on-chip classification dominated the market in terms of revenue, and it is expected to exhibit the fastest growth with more than 45.0% CAGR during the 2018–2025 period. The surging incidents of chronic liver disease and rising research and development activities for therapeutic interventions are the major factors responsible for the growth of this classification.

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For biological research experiments, animal models are presently used that mimic the physiological complexity of the human body at the entire-organism level rather than on a single-organ level. However, the process of using animal models for human disease research is facing complexities related to their translatability to humans and scientific validity. Animal models have displayed poor correlation between animal data and human outcomes, owing to the difference between the species. This is creating the demand for alternatives that can simulate human-relevant conditions. Therefore, organs-on-chips are now being preferred over animal models for disease model studies by researchers.

Thus, the growing need for alternative models for medical research studies is expected to boost the organ-on-chip market progress during the forecast period. Further, the increasing government funding is helping the market players conduct more research activities. Government agencies such as the National Institutes of Health offers grants to facilitate the research programs. For instance, in July 2017, Emulate Inc. declared it had been granted an undisclosed amount to utilize its human Brain-Chip system to create a fully automated research platform for carrying out experiments on the International Space Station.

Hence, the rising demand for alternative models for medical research and growing government support are accelerating the market growth.