Market Spotlight:  Melanoma Disease Coverage 

Disease Overview

The World Health Organization has reported that the incidence of melanoma is increasing faster than that of any other cancer in the world. Melanoma occurs when melanocytes – melanin-producing cells – become malignant. Malignancy of melanocytes in the basal layer of the skin is referred to as primary cutaneous malignant melanoma. Unlike many other common cancers, there is no significant increase in risk for the elderly; instead, the increase in incidence is likely to be due to changes in lifestyle. In particular, the amount of and susceptibility to ultraviolet exposure are key risk factors for malignant melanoma, and are driving the increase in incidence in all age groups.

Market Snapshot

Immunotherapy monotherapies and combination therapies will be the main drivers of growth in the melanoma market over the forecast period.

The introduction of targeted therapies has substantially changed the treatment landscape of melanoma.

Melanoma is a common cancer in the Western world with an increasing incidence, although prognosis is highly variable.

Immune checkpoint inhibitors Yervoy, Opdivo, and Keytruda will be key drivers of growth in the melanoma market.

New developers are targeting NRAS and BRAF mutation-positive patients to distinguish their products, despite the market being limited.

Immunotherapies are changing melanoma treatment paradigms.

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Major TOC Market:

1 FORECAST: MELANOMA

2 Executive Summary
3 Market Overview and Trends
4 Market Definition and Methodology
5 binimetinib
6 Cotellic (cobimetinib)
7 encorafenib
8 Imlygic (talimogene laherparepvec)
9 Keytruda (pembrolizumab)
10 Mekinist (trametinib)
11 Opdivo (nivolumab)
12 Tafinlar (dabrafenib)
13 Yervoy (ipilimumab)
14 Zelboraf (vemurafenib)
15 Primary Research Methodology

16 TREATMENT: MELANOMA
17 Executive Summary
18 Primary Research Methodology
19 Disease Definition and Diagnosis
20 Patient Segmentation
21 Current Treatment Options
22 Prescribing Trends

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LIST OF FIGURES

Figure 1: Melanoma market forecast across the US, Japan, and five major EU markets, by country, 2015–24
Figure 2: Melanoma market forecast across the US, Japan, and five major EU markets, by class, 2015–24
Figure 3: BRAF mutation-positive melanoma market forecast across the US, Japan, and five major EU markets, by country, 2015–24
Figure 4: Branded melanoma market value in the US, 2015–24
Figure 5: Branded melanoma market value in the five major EU markets, by country, 2015–24
Figure 6: Branded melanoma market value in Japan, 2015–24
Figure 7: Methodology flow for Datamonitor Healthcare's melanoma forecast
Figure 8: Price sources and calculations, by country

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