The primary sclerosing cholangitis (PSC) market is characterized by inflammatory and fibrotic strictures of the bile ducts leading to cholestasis. PSC is a progressive disorder of unknown etiology. The signs and symptoms of PSC include jaundice, fatigue, pruritus, abdominal pain and fever. Currently, ursodeoxycholic acid is the only approved therapy for PSC but it only provides relief from symptoms, rather than slowing disease progression. There is no cure for PSC and patients usually ... Read more