Chelating agents are the one which perform chelation.  The High Blood Pressure Program Review   There are several types of chelating agents based on the composition of elements present in them to detoxify the body. People suffering from a heart disease undergo chelation therapy which is an alternative method of treatment to treat a hardened artery. The compound used in the agents is EDTA Enthylenediaminetetraacetic Acid which would react with the heavy metals in the blood and remove toxic.

The doctors found that this method was not that effective in the treatment of coronary heart diseases. Then the National Centre of Complimentary and alternative medicine has begun to conduct trials on chelating agents. This started in the year 2003 and the enrollment for the trial was until July 2009 and it has been extended till July 2010. But the implementation of this trial was stopped in September 2008. The trial did not provide the information on how it would be affecting the people when tried. 

The ethical values had conflicts and hence it was not allowed to carry on this trial. The critics say that the idea of trial has lacked the Phase I and Phase II studies and also it did not show any benefits from the previous use.There are many scientists now that support and prove with their research and reviews that cholesterol is not the causing agent of atherosclerosis. The body of evidence is growing bigger everyday and more scientists on the leading edge of medicine join the side of the obvious truth. But what is the atherosclerosis mechanism then How this debilitating disease does occur and how can we possibly avoid it One man, back in the 70s, was immensely brave to go against the cholesterol craziness and stand alone with his pioneering research proving not only that cholesterol is an innocent molecule but clearly showing the real cause of atherosclerosis Homocysteine. This article is a tribute to Dr Kilmer McCully, the doctor who solved the mystery of atherosclerosis and was brave enough to support his revolutionary findings when the lipid theory was at its peak.

I have dealt with the cholesterol issue in many articles so far. It is not the cause of arteriosclerosis. According to Dr McCully atherosclerosis is a dietary imbalance greatly assisted by the modern type of diet we have adopted. Homocysteine is a natural byproduct of protein metabolism in the body. Specifically the amino acid methionine, which is found in living organisms and we take in with our food, can either be used to synthesize more body proteins or if this is not necessary it converts to homocysteine in the body. Under normal circumstances homocysteine subsequently converts to a water soluble product and is excreted with the urine. The chemical modification takes place in the liver, the powerhouse of detoxification and metabolism. Specific enzymes take part in this process which consists of several separate steps.

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