A list of studies: recent advances in CAR-T cell therapy (part two)

Technology

2. CAR-T with License to Kill Solid Tumors in Search of a Winning Strategy

Doi:10.3390/ijms20081903

Artificial receptors designed for adoptive immunotherapy require dual functions: antigen recognition and the ability to activate lytic machinery of reprogrammed ... Read more

Submitted by import-express on 2019-06-26 08:20.

Introduction to Notch

Technology

There are some antibodies:
1. Brontictuzumab

Recombinant Humanized (from mouse) antibody to Human Notch1.

2. ... Read more

Submitted by import-express on 2019-06-24 10:03.

Introduction to Nerve Growth Factor

Technology

There are two antibodies related to NGF.

1. Fulranumab

Recombinant monoclonal antibody to NGF.Fulranumabis a human monoclonal antibody designed for the treatment of pain ... Read more

Submitted by import-express on 2019-06-21 11:08.

Introduction to antigen and its basic properties (part one)

Technology

Antigen (Ag) refers to all substances that induce an immune response in the body. That is, it can specifically recognize and bind to the antigen receptor (TCR/BCR) on the surface of T/B lymphocytes, and activate T/B cells. A substance that proliferates and differentiates to produce an immune ... Read more

Submitted by import-express on 2019-06-20 09:40.

Protein quantitative analysis technique

Technology

Proteome originates from the combination of protein and genome. It refers to the whole set of proteins expressed by a genome, including all proteins expressed by a cell or even a living creature. Proteomics ... Read more

Submitted by import-express on 2019-06-19 11:32.

Quantitative study of proteomics

Technology

Genome research has made remarkable achievements since it was carried out. In the past few years, complete sequence analysis of genomic DNA of more than a dozen organisms with relatively simple structure, including e. coli, saccharomyces cerebrosaccharides and arabidopsis thaliana, has been ... Read more

Submitted by import-express on 2019-06-17 11:03.

Introduction to cell membrane studies of vesicles

Technology

For some amphiphilic molecules like natural synthetic surfactant can not simply associate the synthesis of micelle phospholipids, dispersed in water will spontaneously form a kind of closed bilayer structure molecular ordered combination, known as vesicles also known as liposome. The meaning of ... Read more

Submitted by import-express on 2019-06-13 11:25.

Immune Responses to Tumors

Technology

Adaptive immune responses, mainly mediated by T cells, have been shown to control the development and progression of malignant tumors. Both innate and adaptive immune responses can be detected in patients and experimental animals, and various immune mechanisms can kill tumor cells in vitro. The ... Read more

Submitted by import-express on 2019-05-27 08:06.

Optimization methods of therapeutic antibodies

Technology

Since FDA approved the first antibody, Orthoclone OKT3, in 1986, more than 70 recombinant antibodies have been approved. There are still hundreds of therapeutic antibodies in clinical research, and the competition in the antibody field is becoming more intense. Therefore, it is necessary to ... Read more

Submitted by import-express on 2019-05-24 05:28.

Study on bile acids and short-chain fatty acids

Technology

Bile acid is the main component in bile, it is the final product of metabolization of cholesterol via liver tissue, when bowel liver circulation is destroyed, bile acid cannot be reused. Carry on principal component ... Read more

Submitted by import-express on 2019-05-23 10:35.

The difference between PD-1 and PD-L1

Technology

What is PD-1 and PD-L1?

PD-1 refers to Programmed Death 1, which is an important immunology inhibitor, a member of CD28 super family. PD-1 targeted immunology ... Read more

Submitted by import-express on 2019-05-22 09:35.

What You Must Know about Cytokine Storms

Technology

Abstract: We often say “cytokine storm”, which is actually a very horrible ... Read more

Submitted by import-express on 2019-05-21 08:58.

Introduction to BCMA

Technology

Firstly, let us see some antibodies.

1. Anti-BCMA-mc-MMAF

This ADC product is composed of an anti-BCMA antibody conjugated via mc linker to MMAF (anti-BCMA-mc-MMAF). It is in Phase ... Read more

Submitted by import-express on 2019-05-20 09:49.

Facts about flow cytometry

Technology

Facts about flow cytometry

Simple Introduction

The full name of FCM is Flow Cytometry. We can also call it FACS whose full name is Fluorescence activated Cell Sorting. It’s a novel analytical technique and separation technique for rapid ... Read more

Submitted by import-express on 2019-05-17 10:49.

How to enhance the activity of ADCC and CDC?

Technology

What is ADCC in immunology？ADCC is the antibody ... Read more

Submitted by import-express on 2019-05-16 10:12.

A brief talk on the cowpox

Technology

Cowpox is an infectious disease occurring in cattle. It is an acute infection caused by smallpox virus. Its symptoms are usually local ulcers in the breast of cows. The virus can be transmitted to humans through contact, mostly in milkers, slaughterhouse workers, patients with skin papules, ... Read more

Submitted by import-express on 2019-05-14 09:00.

Biological switch reliably turns protein expression on at will

Technology

A biological switch that reliably turns protein expression on at will has been invented by University of Bath and Cardiff University scientists. The switch enables control of genome editing tools that might one day regulate cascades of desired genetic changes through entire populations.

Submitted by import-express on 2019-04-28 09:39.

An introduction to proteomics

Technology

Proteome comes from the combination of protein and genome, which means "a complete set of proteins expressed by a genome", that is, all proteins expressed by a cell or even a organism.

There are many similarities between proteome and transcriptome, and they also have space- ... Read more

Submitted by import-express on 2019-04-25 05:14.

A promising tumor immunotherapy technology—Neoantigen

Technology

In the last decade, the field of immunotherapy of tumors has achieved remarkable results: tumor immunotherapy technologies such as PD-1/PD-L1 immunological checkpoint inhibitors and CAR-T cell therapy have been approved for marketing, humans and tumors. On the road of resistance, we will ... Read more

Submitted by import-express on 2019-04-23 07:46.

An overall of Ginsenoside Rb1

Other

An active substance extracted from the dried roots of Araliaceae ginseng, which belongs to tetracyclic triterpenoid saponins, has central nervous system inhibition and stability.

Submitted by import-express on 2019-04-19 08:55.

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