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Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that by right now there are not any long term prescription weightloss pills that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug could also raise blood pressure and heartrate, and shouldn't be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. 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